All the cellular processes in living cells such as growth, development, morphogenesis and cellular differentiation are a product of gene expression programs involving complicated transcriptional reg...

RNA interference (RNAi) is the process of mRNA degradation that is induced by double-stranded RNA in a sequence-specific manner. RNAi has been observed in all eukaryotes, from yeast to mammals. The ...

Early development and differentiation of nascent T cells that migrate from bone marrow to become mature, naïve T cells, which are capable of responding to antigen takes place inside the thymus....

Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. The immune system is the body's defense against infectious organisms an...

FOXP3 is a master regulator of immune homeostasis expressed specifically in CD4+ CD25+ T regulatory cells controlling their growth, development and function. FOXP3 significance in the normal develo...

As a major target for dopamine-activated adenylyl cyclase and protein kinase A in the striatum, DARPP-32 plays a central role in regulating the efficacy of dopaminergic neurotransmission and can act...

ATM, the gene product mutated in the cancer susceptibility syndrome ataxia–telangiectasia, is related to proteins involved in DNA repair and cell-cycle control. It encodes a nuclear 350 kDa ph...

Coined in the 1960's,apoptosisis derived from the Greek word apopiptein which means to fall off from. Apoptosis can be induced by a number of stimuli including UV damage, irradiation, drug treatment...

Akt family of serine/threonine-directed kinases regulates a diverse array of biological processes, including cellular survival, proliferation, glucose homeostasis, and vascular tone and are importan...

Actin is a ubiquitous protein involved in the formation of filaments that are major components of the cytoskeleton. It is the monomeric subunit of microfilaments, one of the three major components o...